Can niacinamide cure alzheimer’s disease_

Last month we received 3 remarkable posts from KH of Las Vegas, USA, who wrote Earth Clinic about her mother’s full recovery from severe dementia while taking niacinamide. Alzheimer’s disease prevention The posts piqued our curiosity, so we asked contributing writer Mary Post to investigate this subject a bit further for our first newsletter of 2014.

While many use the terms ‘Alzheimer’s disease’ and ‘dementia’ interchangeably, technically Alzheimer’s is one form of dementia and is the sixth leading cause of death in the U.S. All about alzheimer’s disease Over 5 million Americans live with this disease, and one-third of seniors die with some form of dementia. Interesting facts about alzheimer’s disease The cost of treating Alzheimer’s is enormous. Alzheimer’s disease journal articles While the documented cost to the nation of treating Alzheimer’s in 2013 was over $203 billion, the unaccounted cost borne by family members was estimated to be over $216 billion in 2012.

According to the Alzheimer’s Association March 2013 Factsheet, someone in the U.S. Physical effects of alzheimer’s disease develops Alzheimer’s every 68 seconds. Treatment alzheimer’s disease Twice as many 70 year olds with Alzheimer’s die before they are 80, compared to 70 year olds who do not have Alzheimer’s. Effects of alzheimer’s disease There is no way to prevent, cure or slow the progression of Alzheimer’s, though the quest for treating Alzheimer’s has spawned a sprawling, world-wide industry, supporting conferences, chains of nursing homes, expensive new drugs, on top of the ongoing costs of the physical care of patients.

Niacinamide has been used safely for at least 60 years, primarily to treat arthritis but also as a treatment for Alzheimer’s. Alzheimer’s disease pathology Psychiatrist and clinical researcher William Kaufman published the first documented account of the use of niacinamide in the treatment of Alzheimer’s in his 1943 publication, The Common Form of Niacin Amide Deficiency Disease: Aniacinamidosis. In his book, he reported that patients who were deficient in niacinamide had the following symptoms: impaired memory, inability to concentrate, difficulty in comprehending and reading, anxiety, uncooperativeness, inability to complete projects or tasks, quarrelsome and dissatisfied.

Alzheimer’s disease description These symptoms, bearing an uncanny resemblance to the symptoms of Alzheimer’s disease, “disappeared… Articles on alzheimer’s disease or improved considerably” on treatment with niacinamide.

Subsequent publications by Kaufman focused on the use of niacinamide in the treatment of degenerative arthritis. Is there a treatment for alzheimer’s disease Kaufman came to the conclusion that niacinamide was not to be seen as a cure but as a permanent supplement, as stopping the dosage brought about the resurgence of the symptoms.

A 2008 study published in the Journal of Neuroscience with demented mice showed that treatment with niacinamide reversed Alzheimer’s by causing a 60% reduction in one of the Alzheimer markers and increasing the number of microtubules that carry information inside the brain cells (1).

A 2013 study concluded that niacinamide prevented cognitive decline in Alzheimer’s mice through improved neuronal activity and reduced breakdown of brain tissue (3).

Jonathon V. Alzheimer’s disease association Wright, M.D. Alzheimer’s disease video reviewed 2008 studies on laboratory mice and concluded that there was no reason to wait for ‘more research’ before administering niacinamide to Alzheimer’s patients (4).

The University of California, Irvine, (conductor of one of the above-mentioned mice studies) is working with the Alzheimer’s Association to study the side effects of treating Alzheimer’s with niacinamide. Late onset alzheimer’s disease This study is scheduled to be completed in June 2014 (5).

Modern-day studies have been based on Kaufman’s findings on dosage. Alzheimer’s disease symptoms and treatment Kauffman argued for the effectiveness of having the dose spread out, as opposed to being administered at one go (6,7).

UK-based physician Dr. Alzheimer’s disease causes Sarah Myhill prescribes niacinamide for a number of problems and reports that though she has never had a patient develop liver problems at high doses (over 500 mg. First signs of alzheimer’s disease daily), she agrees with Kaufman that the best results are achieved by taking low doses regularly spaced throughout the day (8). Alzheimer’s disease brain Bottom Line on the Best Way to Take Niacinamide

If possible, taking 250 mg. Alzheimer’s disease prognosis every 90 minutes, 12 times a day seems to be the best method. What are the physical symptoms of alzheimer disease Sustained release (time release) niacinamide capsules are available on the internet and seem to be a reasonable compromise, though it is important to be aware that these doses are substantially above the Recommended Daily Allowances.

Niacinamide has been used safely for at least 60 years, primarily to treat arthritis, but also as a treatment for Alzheimer’s. Sporadic alzheimer’s disease Studies on mice concluded that niacinamide improved cognition. What are the symptoms of alzheimer’s disease A human study has not yet been completed. Anyone over 60 with a family history of Alzheimer’s and who fears getting the disease might want to consider taking niacinamide as a precaution. Sign of alzheimer’s disease For those already suffering from Alzheimer’s, niacinamide offers hope.

(1) Green KN, Steffan JS, Martinez-Coria H, et al. Protein involved in alzheimer’s disease “Nicotinamide restores cognition in Alzheimer’s disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.” J Neurosci 2008; 28(45): 11,500-11,510

• McCarty MF, Russell AL. Alzheimer disease definition psychology Niacinamide therapy for osteoarthritis–does it inhibit nitric oxide synthase induction by interleukin 1 in chondrocytes? Med Hypotheses. How do you get alzheimer’s disease 1999 Oct;53(4):350-60.

• Pozzilli P, Visalli N, Ghirlanda G, Manna R, Andreani D; Nicotinamide increases C-peptide secretion in patients with recent onset type 1 diabetes. Alzheimer’s disease information Diabet Med 1989 Sep-Oct;6(7):568-72

• Vague P, Vialettes B, Lassmann-Vague V, Vallo J; Nicotinamide may extend remission phase of insulin-dependent diabetes. History of alzheimer’s disease The Lancet Mar 1987 ltr

• Mohler H, Pole P, Cumin R, Pieri L, Kettler R; Nicotinamide is a brain constituent with benzodiazepine-like actions. Stages of alzheimer disease pdf Nature 1979 Apr 5;278(5704):563-5

Mary Post has been researching and writing on health, financial and technical subjects for over thirty years. Health problems suffered by family and friends led to extensive research on health issues, hunting for better answers to their problems. Characteristics of alzheimer’s disease Mary and her husband live near Tampa, Florida.

While it is encouraging to discover that B3 vitamin appears to be helpful in effecting the course of Alzheimer’s positively, yet not completely to the point of reversal or even as a prophylactic, one has to ask the question why there is so much emphasis on one agent, when in fact all chronic diseases are a result of multiple deficiencies. Prognosis of alzheimer’s disease Can people not think in multiple factorials? Or is it mental laziness that prompts people and scientists to want single solutions for diseases which they have decided are a single entity caused by a single factor or agent. Alzheimer’s disease definition All agents that will help to energize brain cells, such as D ribbose, creatine, MSM, coconut oil, coQ10, should be taken into consideration. Alzheimer’s disease is caused by One must also remember that toxins such as aluminium, fluoride and mercury are neurotoxic and probably play a major role in causing mental deterioration. Diagnosis of alzheimer’s disease If such factors are ignored, the research done on any disease becomes null and void and of no value what so ever.

Good comment. The stages of alzheimer’s disease It’s certainly true that there are often multiple causes and remedies for diseases. Alzheimer’s disease diagnosis However, it is very difficult to research multiple items at the same time. Alzheimer’s disease wiki For better or worse, the purpose of any study is to reduce the number or variables to find out is something works. Alzheimer’s disease pictures Drug interactions are very problematic and difficult to track down. How do you test for alzheimer disease Anyone taking multiple medications daily can attest to how difficult it can be to figure out what drug is interacting negatively with another drug. Early onset alzheimer’s disease I don’t know how many Alzheimer’s studies are currently in process, but just today I skimmed over at least 50, all different. What causes alzheimer’s disease Alzheimer’s does not appear to have one cause: some are genetic, some may be environmental, a lot they’re trying to figure out. What are the major symptoms of alzheimer’s disease Research done on one cause or remedy does not invalidate the research. Medical definition of alzheimer’s disease A study is a beginning. What is alzheimer’s disease Research on a medication, for example, cannot investigate drug interactions until they have the drug developed. Alzheimer’s disease symptoms No treatment will work on everyone. What age can you get alzheimer’s disease We are all unique.

Alzheimer’s is certainly a very complicated and horrible disease, especially so to those of us who have watched it first hand destroy someone we loved. Cause of alzheimer’s disease If niacinamide or anything else can help delay the progress for even a few people, IT IS WORTH IT! It’s safe, cheap and has been around for a long time.

DISCLAIMER: Our readers offer information and opinions on Earth Clinic, not as a substitute for professional medical prevention, diagnosis, or treatment. What are the treatment of alzheimer disease Please consult with your physician, pharmacist, or health care provider before taking any home remedies or supplements or following any treatment suggested by anyone on this site. Familial alzheimer’s disease Only your health care provider, personal physician, or pharmacist can provide you with advice on what is safe and effective for your unique needs or diagnose your particular medical history.