Acta dermato-venereologica – chronic urticaria and mild arthritis associated with autoimmune thyroid disease_ successful treatment with l-thyroxine – html hives and children

Treatment with L-thyroxine 50 μg/day was started. Home remedies for hives all over body This dose was escalated by 25 μg every month, up to 125 μg/day. Cure for hives TSH was measured every 1–2 months and remained within 0.4–0.6 µIU/ml. Food hives After 6 weeks of therapy, while taking L-thyroxine 75 μg/day, the patient reported significant improvement, complete withdrawal of pruritus, lymphadenopathy and joint pain. Cure for hives from stress Urticarial rash was still present; however, it was less frequent, with smaller still-confluent areas of wheals, and was not disturbing for the patient. Idiopathic hives causes Further escalation of the dose of L-thyroxine over 75 μg/day did not result in complete disappearance of the rash. Hives on leg All of these effects have lasted 12 months after follow-up.

The decision to apply a non-standard therapy was made due to the disturbing symptoms and lack of response to the previous treatment. What to do if you have hives on your face It is planned to withdraw L-thyroxine substitution gradually over 2 years. Hives internal disease Some authors suggest discontinuing treatment with L-thyroxine gradually within 2 years (3). Allergic reaction toddler hives Others recommend withdrawal of L-thyroxine after improvement is achieved, advising reintroduction of the treatment with recurrence of symptoms (7).

As its mechanism of action is unknown, L-thyroxine treatment in euthyroid patients with ATD associated with systemic symptoms is based on empirical observations and requires further research.


Hives stress pictures The remission of urticaria with such treatment is usually achieved within 2 months, therefore Heymann (1) suggested that a trial of 8 weeks administration of L-thyroxine should be performed in patients with chronic idiopathic urticaria. Thyroid disease and hives Other therapeutic options in unresponsive chronic idiopathic urticaria are: plasmapheresis, intravenous immunoglobulin and cyclosporine (8).

Only a few cases of successful treatment with L-thyroxine of either urticaria (3) or polyarthritis (4) associated with ATD have been published. Images of hives on legs However, to our knowledge, there are no well-documented cases of successful treatment with L-thyroxine of multiple symptoms (joint, skin and other) in one and the same patient. Exercise induced urticaria natural treatment Urticaria may be one of many organ manifestations of a systemic auto-immunological disease with a similar mechanism.

Current opinion is that the presence of thyroid auto-antibodies does not cause urticaria directly (9). Hives treatment causes The presence of a co-existing, but unknown, auto-immunological disorder is possible. Hives causes and treatments Gaig et al. Fever hives cough (3) suggested that keeping the TSH level at the lower range of normal may help to control urticaria. Hives contact dermatitis It is speculated that thyroid stimulation with TSH may take part in the pathogenesis of autoimmune urticaria (7). Dog hives treatment We suggest careful observation of the TSH level during therapy to monitor the effects of treatment and to avoid exogenous hyperthyroidism.

1. Symptoms of hives on neck Heymann WR. Hives on baby feet Chronic urticaria and angioedema associated with thyroid autoimmunity: Review and therapeutic implications. Hormones and hives J Am Acad Dermatol 1999; 40: 229–232.

2. What is hives server ip Lenzoff A, Sussman GL. What causes itchy hives Syndrome of idiopathic chronic urticaria and angioedema with thyroid autoimmunity: a study of 90 patients. Hives virus J Allergy Clin Immunol 1989; 84: 66–71.

3. Food allergy hives duration Gaig P, Garcia-Ortega P, Enrique E, Richart C. Pregnancy hives treatment Successful treatment of chronic idiopathic urticaria associated with thyroid autoimmunity. What causes the hives J Investig Allergol Clin Immunol 2000; 10: 342–345.

4. Recurring hives in same spot LeRiche NG, Bell DA. Home remedy for hives rash Hashimoto’s thyroiditis and polyarthritis: a possible subset of seronegative polyarthritis. Chronic hives treatment Ann Rheum Dis 1984; 43: 594–598.

6. Hives baby treatment Zuberbier T, Greaves MW, Juhlin L, Kobza-Black A, Maurer D, Stingl G, et al. Recurring hives rash Definition, classification, and routine diagnosis of urticaria: a consensus report. Natural remedy hives J Investig Dermatol Symp Proc 2001; 6: 123-127.

7. Hives and rashes on skin Rumbyrt JS, Katz JL, Schocket AL. Hives recurring Resolution of chronic urticaria in patients with thyroid autoimmunity. Hives on feet pictures J Allergy Clin Immunol 1995; 96: 901–905.